| | | Part One |
| Lance Nicholas | Dunne | Amy's husband. Aka: Nick. |
| Amy | Elliot-Dunne | Nick's wife. Missing. |
| Margo | Dunne | Nick's twin sister. Aka: Go. |
| Carmen | | Amy's new friend. |
| Gary | | Margo's tree. |
| McMann | | A bar owner. |
| Carl | Pelley | Nick and Amy's neighbor. |
| Rand | Elliot | Amy's father. A psychologist. |
| Marybeth | Elliot | Amy's mother. |
| Andy | | Amy's fiancé in her book. |
| Velasquez | | A police officer. |
| Riordan | | Velasquez partner. |
| Rhonda | Boney | The lead detective on Amy's missing case. |
| Jim | Gilpin | Boney's partner. |
| Campbell | | Amy's friend. |
| Insley | | Amy's friend. |
| George | | Amy's friend. |
| John | | Amy's friend. |
| Jack | | Nick's friend. |
| Jennifer | | Jack's wife. |
| Jan | Teverer | Nick and Amy's neighbor. |
| Mike | | Nick and Amy's neighbor. |
| Taylor | | One of Mike's daughters. |
| Talullah | | One of Mike's daughters. |
| Topher | | Mike's son. |
| Geraldine | Ferraro | A vice presidential candidate in 1984. |
| Ellen | Abbott-Live | Specialized in missing and murdered women. |
| Hannah | | Nick's alleged side chick. |
| Brian | | Amy's friend in Amazing Amy. |
| Suzy | | Brian's friend. Amazing Amy's sidekick. |
| Joanna | | Amy's archrival in the Amazing Amy book. |
| Judith | Viorst | A character in Amazing Amy. |
| Hilary | Handy | The girl who was obsessed with the Amazing Amy book. |
| Desi | Collings | Amy's ex-boyfriend who became obsessed with her. |
| Stucks | Buckley | Nick's old friend. |
| Shawna | Kelly | The frito-pie baker. |
| Mr. | Coleman | Nick's former teacher. |
| Joe | Hillsam | Mikey's brother. |
| Mikey | Hillsam | Joe's brother. The town's badass. |
| Lonnie | | Drug and illegal firearms dealer. |
| Maureen | Dunne | Nick's mother. Aka: Mo. |
| Vicky | | Maureen's best friend. |
| Bill | Dunne | Nick's father. |
| Noelle | Hawthorne | Amy's best friend. |
| Andie | | Nick's mistress. |
| Mary | | One of Amy's friends. |
| Blecker | | Amy's cat. |
| Jacqueline | Collings | Desi's mother. |
| David | Samson | One of Amy's ex-boyfriends. |
| Murphy | Clark | One of Amy's ex-boyfriends. |
| Tanner | Bolt | Nick's lawyer. Aka: Hubby Hawk, Dickhead Defender. |
| Cody | Olsen | Tanner's former client. |
| | | Part Two |
| Dorothy | | The Walmart manager. |
| Jeff | | Amy's new boyfriend. |
| Madeleine | | Andie's friend. |
| Greta | | The girl that Amy met. |
| Campbell | McIntosh | Amy's childhood friend. |
| Rebecca | | The girl who wanted to interview Nick. |
| Sharon | Schieber | A reporter. |
| Betsy | Bolt | Tanner's wife. |
| Custer | | A police officer. |